UNC Neuroscience Center and the BRAIN Initiative Viral Vector Core

Affordable, Custom Viral Vectors for Neuroscience

Offering: AAV, Rabies, Lenti, and HSV

Get vector design, production, and performance optimization tailored for your work:

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AAV labeling of three classes of mossy fiber inputs to the cerebellum.

Adeno-associated virus (AAV)

  • custom expression vector/capsid combinations

  • small prep sizes (100ul, 500ul)

  • CsCl density gradient purified (2-3 rounds depending on need)

  • custom titer requests

  • long expression construct packaging (up to 6.5KB ITR-ITR)

AAV labeling of three classes of mossy fiber inputs to the cerebellum. Hantman Lab

 

Rabies (Rbv)

  • CVS-N2c and SADB19 G-deleted expression constructs.

  • pseudo typed with CVS-N2c-G, SADB19-G, EnvA, or EnvB

  • complimenting AAV constructs

  • guidance for decreasing toxicity

Rabies labeling of inputs to the pontine nucleus. Huang et. al

 
NeuRet (L) and HiRet (R) in striatum.

Lenti-virus (LV)

  • VSV-G psuedotyped

  • NeuRet/HiRet

  • prep purity for culture or in-vivo applications.

NeuRet (L) and HiRet (R) labeling in striatum. Martin Bohlen, Sommers Lab